The mission of the Stanford-SLAC Cryo-EM Center (S2C2) is to provide:
- Access to state-of-the-art instrumentation for specimen vitrification and cryo-EM data collection towards atomic resolution structure determination.
- Support in screening and optimization of vitrified samples.
- Training to enable scientists to become independent cryo-EM investigators.
Our Center has cryo-specimen preparation devices, data quality assessment tools for on-the-fly evaluation and visualization, and image data storage capacity. Our expert staff also train, assist and advise users, both on-site and remotely, and are available for consultation beforehand and for follow-up discussions. We cross-train scientists who want to employ cryo-EM within their own research portfolios. Our training - including short-term and long-term in-residence programs for single particle cryo-EM workflow, from specimen preparation to structure validation, is targeted at a wide variety of skill levels. Access to the Center is through an open process based on scientific merit.
Project applications for S2C2 are due on the first day of each month and are generally reviewed within the same month.