Mission Statement:

The mission of the Stanford-SLAC Cryo-EM Center (S²C²) is to provide:

• Access to state-of-the-art instrumentation for specimen vitrification and cryo-EM data collection towards atomic resolution structure determination.
• Support in screening and optimization of vitrified samples.
• Training to enable scientists to become independent cryo-EM investigators.

Our Center has cryo-specimen preparation devices, data quality assessment tools for on-the-fly evaluation and visualization, and image data storage capacity. Our expert staff also train, assist and advise users, both on-site and remotely, and are available for consultation beforehand and for follow-up discussions. We cross-train scientists who want to employ cryo-EM within their own research portfolios. Our training - including short-term and long-term in-residence programs for single particle cryo-EM workflow, from specimen preparation to structure validation, is targeted at a wide variety of skill levels.  Access to the Center is through an open process based on scientific merit.

Project applications for S²C² are due on the first day of each month and are generally reviewed within the same month.

Read about S²C² »Apply to use the cryo-EM facilities »